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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924673Generated: October 31, 2026

5-Hydrazinylquinoline → 1-(3-Difluoromethoxy-phenyl)-3-(2-quinolin-5-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-one

https://huagongshe.com/reaction/1924673

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-HydrazinylquinolineHCID 5200451—
Reactant1-(3-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-oneHCID 59370014—
Product1-(3-Difluoromethoxy-phenyl)-3-(2-quinolin-5-yl-2H-pyrazol-3-yl)-1H-pyridazin-4-oneHCID 59369993—

Reaction Steps

The product was obtained starting from 1-(3-Difluoromethoxy-phenyl)-3-((E)-3-dimethylamino-acryloyl)-1H-pyridazin-4-one (A-10) and quinolin-5-yl-hydrazine according to the method described for example 91. MS: M=432.2 (M+H)+

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178538B2
Source datasetuspto-grants-2012_05
ORD IDord-7bcee78f949844248eceda46b03b92eb
Source noteuspto-grants-2012_05