HCID 45117037, compound → HCID 59369985, compound

HRID 1924694Notes

Reaction equation

HRID 1924694 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=2)[N:8]=1)=O.[CH:26]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:29]([NH:36][NH2:37])=[CH:28][N:27]=1>>[CH:26]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:29]([N:36]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:15]=[CH:16][C:17]([O:20][C:21]([F:22])([F:24])[F:23])=[CH:18][CH:19]=4)[N:8]=3)=[CH:4][CH:3]=[N:37]2)=[CH:28][N:27]=1

Participants

3

Reactant 2

HCID 45117037HCID 45117037, compoundHCID 593700343-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one

Product 1

HCID 59369985HCID 59369985, compound

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and isoquinolin-4-yl-hydrazine according to the method described for example 91. MS: M=450.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-d8b0550cb2054b3cad4e8d125d12cfe3
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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