HCID 5704110, compound → HCID 59370042, compound
Reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([C:20]([F:23])([F:22])[F:21])=[CH:16][CH:15]=2)[N:8]=1)=O.[Cl:25][C:26]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:29]([NH:36][NH2:37])=[CH:28][CH:27]=1>>[Cl:25][C:26]1[C:35]2[C:30](=[CH:31][CH:32]=[CH:33][CH:34]=2)[C:29]([N:36]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][C:17]([C:20]([F:22])([F:21])[F:23])=[CH:16][CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:37]2)=[CH:28][CH:27]=1Participants
3
Procedure
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethyl-phenyl)-1H-pyridazin-4-one (A-22) and (4-chloro-naphthalen-1-yl)-hydrazine according to the method described for example 1. MS: M=467.2 (M+H)+
Workup
- customThe product was obtained
Sources & evidence
- ORD record
- ord-d96a55fcaf5042b2b1845f89921efb99
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08178538B2
Reaction notes
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