3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one → HCID 59370009, compound

HRID 1924715Notes

Reaction equation

HRID 1924715 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([O:20][C:21]([F:24])([F:23])[F:22])=[CH:16][CH:15]=2)[N:8]=1)=O.[NH:26]([C:28]1[CH:33]=[CH:32][N:31]=[C:30]([C:34]([F:37])([F:36])[F:35])[CH:29]=1)[NH2:27]>>[F:23][C:21]([F:22])([F:24])[O:20][C:17]1[CH:16]=[CH:15][C:14]([N:9]2[CH:10]=[CH:11][C:12](=[O:13])[C:7]([C:5]3[N:26]([C:28]4[CH:33]=[CH:32][N:31]=[C:30]([C:34]([F:37])([F:35])[F:36])[CH:29]=4)[N:27]=[CH:3][CH:4]=3)=[N:8]2)=[CH:19][CH:18]=1

Participants

3

Reactant 2

HCID 593700343-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-oneHCID 674237204-Hydrazinyl-2-(trifluoromethyl)pyridine

Product 1

HCID 59370009HCID 59370009, compound

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethoxy-phenyl)-1H-pyridazin-4-one (A-8) and 4-hydrazino-2-trifluoromethylpyridine according to the method described for example 91. MS: M=468.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-3cfbbb1f02364aedaf0af1258799b511
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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