5-Hydrazinylisoquinoline → HCID 46220258, compound

HRID 1924716Notes

Reaction equation

C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=2)[C:17]#[N:18])[N:8]=1)=O.[CH:23]1[C:32]2[C:27](=[C:28]([NH:33]N)[CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][N:24]=1>>[CH:23]1[C:32]2[C:27](=[C:28]([N:33]3[C:5]([C:7]4[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]5[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=5)[C:17]#[N:18])[N:8]=4)=[CH:4][CH:3]=[N:2]3)[CH:29]=[CH:30][CH:31]=2)[CH:26]=[CH:25][N:24]=1

Participants

Reactant 2

HCID 132664235-Hydrazinylisoquinoline

HCID 59370150HCID 59370150, compound

Product 1

HCID 46220258HCID 46220258, compound

Procedure

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-benzonitrile (A-19) and isoquinolin-5-yl-hydrazine according to the method described for example 91. MS: M=391.2 (M+H)+

Workup

customThe product was obtained

Sources & evidence

ORD record: ord-8f5cd00d7b144d9a91ae53b2b19322f4
Source dataset: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08178538B2

Reaction notes

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