7-Chloro-4-hydrazinylquinoline → HCID 59370017, compound
Reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=2)[C:17]#[N:18])[N:8]=1)=O.[Cl:23][C:24]1[CH:33]=[C:32]2[C:27]([C:28]([NH:34]N)=[CH:29][CH:30]=[N:31]2)=[CH:26][CH:25]=1>>[Cl:23][C:24]1[CH:33]=[C:32]2[C:27]([C:28]([N:34]3[C:5]([C:7]4[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]5[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=5)[C:17]#[N:18])[N:8]=4)=[CH:4][CH:3]=[N:2]3)=[CH:29][CH:30]=[N:31]2)=[CH:26][CH:25]=1Participants
3
Procedure
The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-benzonitrile (A-19) and (7-chloro-quinolin-4-yl)-hydrazine according to the method described for example 91. MS: M=425.1 (M+H)+
Workup
- customThe product was obtained
Sources & evidence
- ORD record
- ord-6369e36b8ab24165b935737a8229caf9
- Source dataset
- uspto-grants-2012_05
- Patent number
- US08178538B2
Reaction notes
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