4-Hydrazinoquinoline → HCID 46209520, compound

HRID 1924727Notes

Reaction equation

HRID 1924727 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([O:20][CH2:21][C:22]([F:25])([F:24])[F:23])=[CH:16][CH:15]=2)[N:8]=1)=O.[N:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[C:30]([NH:37][NH2:38])=[CH:29][CH:28]=1>>[N:27]1[C:36]2[C:31](=[CH:32][CH:33]=[CH:34][CH:35]=2)[C:30]([N:37]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][C:17]([O:20][CH2:21][C:22]([F:25])([F:23])[F:24])=[CH:16][CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:38]2)=[CH:29][CH:28]=1

Participants

3

Reactant 2

HCID 70204114-HydrazinoquinolineHCID 59370013HCID 59370013, compound

Product 1

HCID 46209520HCID 46209520, compound

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-[4-(2,2,2-trifluoro-ethoxy)-phenyl]-1H-pyridazin-4-one (A-32) and quinolin-4-yl-hydrazine according to the method described for example 43. MS: M=464.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-baf5e4f6294b4119a4e6010cde3ca1aa
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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