4-Hydrazino-2-methylpyridine → 3-{3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

HRID 1924728Notes

Reaction equation

HRID 1924728 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=2)[C:17]#[N:18])[N:8]=1)=O.[NH:23]([C:25]1[CH:30]=[CH:29][N:28]=[C:27]([CH3:31])[CH:26]=1)N>>[CH3:31][C:27]1[CH:26]=[C:25]([N:23]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=4)[C:17]#[N:18])[N:8]=3)=[CH:4][CH:3]=[N:2]2)[CH:30]=[CH:29][N:28]=1

Participants

3

Reactant 2

HCID 200736634-Hydrazino-2-methylpyridineHCID 59370150HCID 59370150, compound

Product 1

HCID 593700723-{3-[2-(2-Methyl-pyridin-4-yl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

Procedure

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-benzonitrile (A-19) and 4-hydrazino-2-methylpyridine according to the method described for example 91. MS: M=355.2 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-3779b40893564badaa906059d7841085
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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