2,5-Difluorophenylhydrazine → HCID 59370128, compound

HRID 1924743Notes

Reaction equation

HRID 1924743 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([N:23]3[CH2:27][CH2:26][CH2:25][CH2:24]3)(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[F:29][C:30]1[CH:35]=[CH:34][C:33]([F:36])=[CH:32][C:31]=1[NH:37]N>>[F:29][C:30]1[CH:35]=[CH:34][C:33]([F:36])=[CH:32][C:31]=1[N:37]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([N:23]4[CH2:24][CH2:25][CH2:26][CH2:27]4)(=[O:22])=[O:21])[CH:15]=3)[N:8]=2)=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 5889572,5-DifluorophenylhydrazineHCID 59370023HCID 59370023, compound

Product 1

HCID 59370128HCID 59370128, compound

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-[3-(pyrrolidine-1-sulfonyl)-phenyl]-1H-pyridazin-4-one (A-29) and 2,5-difluoro-phenylhydrazine according to the method described for example 91. MS: M=484.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-e0252016588b430b98c02abd0f3f0035
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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