(2,3-Dichlorophenyl)hydrazine → 3-[2-(2,3-Dichloro-phenyl)-2H-pyrazol-3-yl]-1-(4-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

HRID 1924748Notes

Reaction equation

HRID 1924748 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][C:17]([S:20]([C:23]([F:26])([F:25])[F:24])(=[O:22])=[O:21])=[CH:16][CH:15]=2)[N:8]=1)=O.[Cl:28][C:29]1[C:34]([Cl:35])=[CH:33][CH:32]=[CH:31][C:30]=1[NH:36]N>>[Cl:28][C:29]1[C:34]([Cl:35])=[CH:33][CH:32]=[CH:31][C:30]=1[N:36]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:19]=[CH:18][C:17]([S:20]([C:23]([F:24])([F:25])[F:26])(=[O:22])=[O:21])=[CH:16][CH:15]=3)[N:8]=2)=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 600691(2,3-Dichlorophenyl)hydrazineHCID 593701663-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one

Product 1

HCID 462203643-[2-(2,3-Dichloro-phenyl)-2H-pyrazol-3-yl]-1-(4-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(4-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one (A-27) and 2,3-dichloro-phenylhydrazine according to the method described for example 1. MS: M=515.0 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-c3437645dcd9430086877ea2a22750e3
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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