(3-Chlorophenyl)hydrazine → 3-[2-(3-Chloro-phenyl)-2H-pyrazol-3-yl]-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

HRID 1924751Notes

Reaction equation

HRID 1924751 reaction equation
CN(C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([C:23]([F:26])([F:25])[F:24])(=[O:22])=[O:21])[CH:15]=2)[N:8]=1)=O.[Cl:28][C:29]1[CH:30]=[C:31]([NH:35][NH2:36])[CH:32]=[CH:33][CH:34]=1>>[Cl:28][C:29]1[CH:30]=[C:31]([N:35]2[C:5]([C:7]3[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]4[CH:19]=[CH:18][CH:17]=[C:16]([S:20]([C:23]([F:26])([F:24])[F:25])(=[O:22])=[O:21])[CH:15]=4)[N:8]=3)=[CH:4][CH:3]=[N:36]2)[CH:32]=[CH:33][CH:34]=1

Participants

3

Reactant 2

HCID 75332(3-Chlorophenyl)hydrazineHCID 593701323-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one

Product 1

HCID 675212013-[2-(3-Chloro-phenyl)-2H-pyrazol-3-yl]-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one

Procedure

The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one (A-33) and 3-chloro-phenylhydrazine according to the method described for example 1. MS: M=481.0 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-77d326471ffd4b7eabf95476aaf3cc33
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

Loading…