2-Fluorophenylhydrazine hydrochloride → 3-{3-[2-(2-Fluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

HRID 1924753Notes

Reaction equation

HRID 1924753 reaction equation
C[N:2](C)/[CH:3]=[CH:4]/[C:5]([C:7]1[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]2[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=2)[C:17]#[N:18])[N:8]=1)=O.[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[NH:30]N>>[F:23][C:24]1[CH:29]=[CH:28][CH:27]=[CH:26][C:25]=1[N:30]1[C:5]([C:7]2[C:12](=[O:13])[CH:11]=[CH:10][N:9]([C:14]3[CH:15]=[C:16]([CH:19]=[CH:20][CH:21]=3)[C:17]#[N:18])[N:8]=2)=[CH:4][CH:3]=[N:2]1

Participants

3

Reactant 2

HCID 4238442-Fluorophenylhydrazine hydrochlorideHCID 59370150HCID 59370150, compound

Product 1

HCID 593701163-{3-[2-(2-Fluoro-phenyl)-2H-pyrazol-3-yl]-4-oxo-4H-pyridazin-1-yl}-benzonitrile

Procedure

The product was obtained starting from 3-[3-((E)-3-Dimethylamino-acryloyl)-4-oxo-4H-pyridazin-1-yl]-benzonitrile (A-19) and 2-fluoro-phenylhydrazine according to the method described for example 1. MS: M=358.1 (M+H)+

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-cfbe272646b34f2889beb97709984b41
Source dataset
uspto-grants-2012_05
Patent number
US08178538B2

Reaction notes

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