HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Chloro-2-fluorophenyl)hydrazine → 3-[2-(3-Chloro-2-fluoro-phenyl)-2H-pyrazol-3-yl]-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Chloro-2-fluorophenyl)hydrazine | HCID 2778381 | — |
| Reactant | 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370132 | — |
| Product | 3-[2-(3-Chloro-2-fluoro-phenyl)-2H-pyrazol-3-yl]-1-(3-trifluoromethanesulfonyl-phenyl)-1H-pyridazin-4-one | HCID 59370167 | — |
Reaction Steps
The product was obtained starting from 3-((E)-3-Dimethylamino-acryloyl)-1-(3-trifluoromethansulfonyl-phenyl)-1H-pyridazin-4-one (A-33) and 3-chloro-2-fluoro-phenylhydrazine according to the method described for example 1. MS: M=499.0 (M+H)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178538B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-e09481eeffaf40c1835077646ffc58e7 |
| Source note | uspto-grants-2012_05 |