HuagongsheHuagongshe Chemistry Print Report · For research reference only
(3-Methylpyridin-4-yl)boronic acid → HCID 44548776, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (3-Methylpyridin-4-yl)boronic acid | HCID 44754762 | — |
| Reactant | N-(5-bromothiazolo[5,4-b]pyridin-2-yl)-4-(1-hydroxy-2-methylpropan-2-yl)benzamide | HCID 58015383 | — |
| Product | HCID 44548776 | HCID 44548776 | 70% |
Reaction Steps
The titled compound (yield=70%) was prepared using a procedure analogous to that described in connection with 9 (Example 9) except 2F (Example 2) and 3-methylpyridin-4-ylboronic acid were used as starting materials. 1H NMR (400 MHz, DMSO-d6) δ ppm 1.21 (s, 6H) 2.47 (s, 3H) 3.42 (s, 2H) 7.52 (d, J=8.59 Hz, 2H) 7.81-7.90 (m, 2H) 8.04 (d, J=8.59 Hz, 2H) 8.26 (d, J=8.34 Hz, 1H) 8.69 (d, J=4.29 Hz, 1H) 8.75 (br. s., 1H) 13.05 (br. s., 1H); ESI-MS: m/z 419.0 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178555B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-be4c5f07bf1f46a8a1696aeda35ee6ae |
| Source note | uspto-grants-2012_05 |