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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1924877Generated: October 26, 2026

Creatine → Creatine Dinitrate

https://huagongshe.com/reaction/1924877

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCreatineHCID 586—
ReactantNitric AcidHCID 944—
ReactantCreatine NitrateHCID 25231507—
SolventWaterHCID 962—
ProductCreatine DinitrateHCID 86628844—
ProductCreatine TrinitrateHCID 86628845—

Reaction Steps

Applicants have cost-effectively synthesized Creatine Nitrate by combining nitric acid and Creatine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Creatine Dinitrate or Creatine Trinitrate. An alternative implementation may comprise using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Creatine Nitrite. Creatine Nitrite has the same effects as Creatine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Creatine Nitrate-Orotate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178572B2
Source datasetuspto-grants-2012_05
ORD IDord-cf901c1211b74ff1a711a94cdfdecb70
Source noteuspto-grants-2012_05