Nitric Acid → HCID 86628855, compound

HRID 1924881Notes

Reaction equation

HRID 1924881 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:11]([OH:13])=[O:12])[CH2:7][CH2:8][CH2:9][NH2:10].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:18][C@H:19]([C:24]([OH:26])=[O:25])[CH2:20][CH2:21][CH2:22][NH2:23]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:14]([O-:17])([OH:16])=[O:15].[NH2:5][C@H:6]([C:11]([OH:13])=[O:12])[CH2:7][CH2:8][CH2:9][NH2:10].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:18][C@H:19]([C:24]([OH:26])=[O:25])[CH2:20][CH2:21][CH2:22][NH2:23]

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 6262L-(-)-OrnithineHCID 86628857HCID 86628857, compound

Product 2

HCID 86628855HCID 86628855, compoundHCID 86628856HCID 86628856, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Applicants have cost-effectively synthesized Ornithine Nitrate by combining nitric acid and Ornithine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Ornithine Dinitrate or Ornithine Trinitrate. An alternative implementation comprises using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Ornithine Nitrite. Ornithine Nitrite has the same effects as Ornithine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Ornithine Nitrate-Orotate.

Workup

  1. customleaving
  2. customto crystallize

Sources & evidence

ORD record
ord-05046a6e0e0a43f19023bff97c0319f0
Source dataset
uspto-grants-2012_05
Patent number
US08178572B2

Reaction notes

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