4-(1-(4-fluorobenzyl)-1H-benzoimidazol-2-yl)-4-hydroxypiperidine → 1-(3,4,5-Trimethoxy-benzyl)-3-[2-[4-[1-(4-fluoro-benzyl)-1H-benzoimidazol-2-yl]-4-hydroxy-piperidin-1-yl]-ethyl]-3-(phenylmethyl)-2-oxo-pyrrolidine
Reaction equation
[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:25])[C:9]([CH2:12][CH2:13][S:14]([CH3:15])(=[O:16])=[O:17])([CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:26][c:27]([O:31][CH3:32])[c:28]1[O:29][CH3:30].[F:33][c:34]1[cH:35][cH:36][c:37]([CH2:38][n:39]2[c:40]([C:48]3([OH:54])[CH2:49][CH2:50][NH:51][CH2:52][CH2:53]3)[n:41][c:42]3[c:43]2[cH:44][cH:45][cH:46][cH:47]3)[cH:55][cH:56]1>>[CH3:1][O:2][c:3]1[cH:4][c:5]([CH2:6][N:7]2[C:8](=[O:25])[C:9]([CH2:12][CH2:13][N:51]3[CH2:50][CH2:49][C:48]([c:40]4[n:39]([CH2:38][c:37]5[cH:36][cH:35][c:34]([F:33])[cH:56][cH:55]5)[c:43]5[c:42]([n:41]4)[cH:47][cH:46][cH:45][cH:44]5)([OH:54])[CH2:53][CH2:52]3)([CH2:18][c:19]3[cH:20][cH:21][cH:22][cH:23][cH:24]3)[CH2:10][CH2:11]2)[cH:26][c:27]([O:31][CH3:32])[c:28]1[O:29][CH3:30]Participants
3
Reactant 2
Product 1
Sources & evidence
- ORD record
- ord-45fb2c54ee234180b9ce59f3b19f2d34
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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