HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 2727950, compound → (5-Amino-2-morpholinophenyl)methanol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 2727950 | HCID 2727950 | — |
| Catalyst | Palladium hydroxide | HCID 9942167 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | (5-Amino-2-morpholinophenyl)methanol | HCID 23136616 | 84.2% |
Reaction Steps
To a solution of (2-morpholin-4-yl-5-nitro-phenyl)-methanol (870 mg) in ethanol (40 mL), palladium hydroxide (87 mg) is added and the mixture is stirred in a Parr-apparatus under hydrogen pressure (10 bars) for 4 hours. The reaction mixture is filtrated over Celite 521, washed with ethanol and concentrated in vacuo to give the title compound (640 mg, 83%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178530B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-5bdbf893d3574d7e978dcf3c26f995cc |
| Source note | uspto-grants-2012_05 |