HCID 57580664, compound → HCID 59022996, compound

HRID 1925010Notes

Reaction equation

HRID 1925010 reaction equation
C(N1CCC(C2C=CC(N[C:17]3[C:18]4[N:19]([CH:33]=[CH:34][N:35]=4)[C:20]([C:23]4[CH:24]=[C:25]5[C:29](=[CH:30][CH:31]=4)[C:28](=[O:32])[NH:27][CH2:26]5)=[CH:21][N:22]=3)=CC=2)CC1)(C)C.[CH:36]([N:39]1[CH2:44][CH2:43][N:42]([C:45]2[CH:50]=[CH:49][C:48]([NH2:51])=[CH:47][C:46]=2[C:52]([F:55])([F:54])[F:53])[CH2:41][CH2:40]1)([CH3:38])[CH3:37]>>[CH:36]([N:39]1[CH2:40][CH2:41][N:42]([C:45]2[CH:50]=[CH:49][C:48]([NH:51][C:17]3[C:18]4[N:19]([CH:33]=[CH:34][N:35]=4)[C:20]([C:23]4[CH:24]=[C:25]5[C:29](=[CH:30][CH:31]=4)[C:28](=[O:32])[NH:27][CH2:26]5)=[CH:21][N:22]=3)=[CH:47][C:46]=2[C:52]([F:55])([F:54])[F:53])[CH2:43][CH2:44]1)([CH3:38])[CH3:37]

Participants

3

Reactant 2

HCID 57580664HCID 57580664, compoundHCID 59023041HCID 59023041, compound

Product 1

HCID 59022996HCID 59022996, compound

Procedure

This compound may be prepared using the methods as described for Compound 206, using 4-(4-isopropylpiperazin-1-yl)-3-(trifluoromethyl)phenylamine in Step 3. LCMS: Rt=0.98 min (95%), m/z 536 (M+H)+.

Workup

  1. customThis compound may be prepared

Sources & evidence

ORD record
ord-47e6e705cf02446ea7fd790a120e1fc1
Source dataset
uspto-grants-2012_05
Patent number
US08178530B2

Reaction notes

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