HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → Hexahydrocyclopenta(c)pyrrol-5(1H)-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | tert-Butyl 5-oxohexahydrocyclopenta(c)pyrrole-2(1H)-carboxylate | HCID 10998690 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | Hexahydrocyclopenta(c)pyrrol-5(1H)-one | HCID 46911901 | — |
Reaction Steps
reacting starting material 5-oxo-hexahydro-cyclopenta[c]pyrrole-2-carboxylic acid tert-butyl ester (I-1a) with trifluoroacetic acid in the solvent of dichloromethane in an ice-water bath to obtain hexahydro-cyclopenta[c]pyrrol-5-one triflutate (I-1b);
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178575B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-8c1cbdffad434e8a81e4705f0b105b40 |
| Source note | uspto-grants-2012_05 |