HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-6,7-dimethoxyquinazoline → Phenylmethyl 6-((6,7-bis(methoxy)-4-quinazolinyl)oxy)-2-naphthalenylcarbamate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-6,7-dimethoxyquinazoline | HCID 2769364 | — |
| Reactant | benzyl N-(6-hydroxynaphthalen-2-yl)carbamate | HCID 67520229 | — |
| Product | Phenylmethyl 6-((6,7-bis(methoxy)-4-quinazolinyl)oxy)-2-naphthalenylcarbamate | HCID 59813744 | — |
Reaction Steps
N-(6-Hydroxy-2-naphthyl)(phenylmethoxy)carboxamide (180 mg, 0.61 mmol, Example 1a) was reacted with 4-chloro-6,7-dimethoxy-quinazoline (140 mg, 0.61 mmol, Oakwood) under the conditions of Example 4b to give the title compound as a white solid. MS (ESI, pos. ion) m/z: 482.5 (M+1). Mass Calc'd for C28H23N3O5: 481.16.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178557B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-890337770ad24a91b3cd15d04c073b75 |
| Source note | uspto-grants-2012_05 |