HuagongsheHuagongshe Chemistry Print Report · For research reference only
Thionyl Chloride → HCID 86608625, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Thionyl Chloride | HCID 24386 | — |
| Reactant | HCID 24822778 | HCID 24822778 | — |
| Product | HCID 86608625 | HCID 86608625 | — |
Reaction Steps
A suspension of 6-(6,7-dimethoxyquinolin-4-yloxy)-5-fluoro-1-naphthoic acid (1.23 g, 3.12 mmol) in thionyl chloride (3 mL, excess) was refluxed for 1.5 h. The reaction mixture was concentrated in-vacuo and azeotroped with toluene (×2) to give the title compound as a brown solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178557B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-368a806f324e4a289a299df69e491761 |
| Source note | uspto-grants-2012_05 |