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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925380Generated: October 30, 2026

tert-Butyl 6-amino-3,3-dimethyl-2,3-dihydro-1H-indole-1-carboxylate → HCID 67520392, compound

https://huagongshe.com/reaction/1925380

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl 6-amino-3,3-dimethyl-2,3-dihydro-1H-indole-1-carboxylateHCID 50999068—
ReactantHCID 178418361HCID 178418361—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 67520392HCID 67520392—

Reaction Steps

To a mixture of tert-butyl 6-amino-3,3-dimethylindoline-1-carboxylate (500 mg, 1.9 mmol) in MeOH (25 mL), under nitrogen, Pd/C (wet w/MeOH) was added and the atmosphere changed to hydrogen. The reaction mixture was stirred at RT for 3 h. The reaction mixture was filtered through a pad of celite and evaporated to give the title compound as a thick liquid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178557B2
Source datasetuspto-grants-2012_05
ORD IDord-3b60720224514d199acf7190583d315e
Source noteuspto-grants-2012_05