Iodoethane → HCID 86633391, compound

Participants

Reaction Steps

Compound 207 was N-ethylated as in Example 82, using iodoethane instead of iodomethane, to give Compound 253. 1H NMR (300 MHz, CDCl3) δ 8.60 (s, 1H), 8.22 (d, J=68 Hz, 2H), 7.83 (d, J=8.8 Hz, 2H), 7.41 (d, J=9 Hz, 2H), 7.39 (d, J=8.6 Hz, 2H), 6.17 (s, 1H), 3.8 (q, J=7.5 Hz, 2H), 3.60-3.30 (m, 11H), 3.10 (br s, 1H), 1.38 (d, J=6.0 Hz, 3H), 1.20 (t, J=7.5 Hz, 3H); MS 659.12 ([M+H]+).

Provenance & Evidence