HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tert-butyl (2-{4-[2-(1-adamantyl)ethoxy]phenyl}ethyl)-carbamate → (2-{4-[2-(1-Adamantyl)ethoxy]phenyl}ethyl)amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tert-butyl (2-{4-[2-(1-adamantyl)ethoxy]phenyl}ethyl)-carbamate | HCID 86649157 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | (2-{4-[2-(1-Adamantyl)ethoxy]phenyl}ethyl)amine | HCID 67520640 | — |
Reaction Steps
Obtained from Intermediate 21 (0.167 g, 1.42 mmol) in hydrogen chloride 1.25M in methanol by the same procedure described in Intermediate 17. The solvent was removed to give the title compound as a white solid salt (0.127 g, 98%), which was used in the next step without further purification. MS (M+): 300.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178679B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-d5fcafff68ed4960823637c5680dca13 |
| Source note | uspto-grants-2012_05 |