Hydrochloric Acid → HCID 42623936, compound

Participants

Reaction Steps

To a solution of Intermediate 43 (0.075 g, 0.13 mmol) in a mixture of methanol (3 mL) and tetrahydrofuran (1 mL) was added some drops of hydrogen chloride 1.25M in methanol and palladium on charcoal (10%, 0.015 g). The reaction mixture was hydrogenated under a balloon pressure overnight. The catalyst was filtered through Celite® and the solvent removed under reduced pressure. The crude was treated with ether and collected by filtration to obtain the title compound as a yellow solid (0.055 g, 82%).

Provenance & Evidence