HuagongsheHuagongshe Chemistry Print Report · For research reference only
Benzene, (3-iodopropyl)- → 2-(4-Phenylbutyl)nicotinic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Benzene, (3-iodopropyl)- | HCID 138121 | — |
| Reactant | 2-Methylnicotinic acid | HCID 643373 | — |
| Product | 2-(4-Phenylbutyl)nicotinic acid | HCID 67134191 | 75.3% |
Reaction Steps
Starting from 2.1 g (15.0 mmol) of 2-methyl-nicotinic acid and 5.5 g (22.5 mmol) of 1-iodo-3-phenyl-propane, 2.9 g (11.3 mmol, 75%) of 2-(4-phenylbutyl)nicotinic acid were obtained according to the process described in precursor VB006.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178684B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-45e8c2957b584bc39b87fd0f6dc167d7 |
| Source note | uspto-grants-2012_05 |