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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925602Generated: October 29, 2026

Prolinamide, D- → 1-{[3-(4-{[4-[5-Fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-prolinamide

https://huagongshe.com/reaction/1925602

Reaction equation

Participants

RoleNameHCIDCharge
ReactantProlinamide, D-HCID 447554—
Reactant3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acidHCID 25180783—
Product1-{[3-(4-{[4-[5-Fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)phenyl]carbonyl}-D-prolinamideHCID 24782414—

Reaction Steps

Prepared similarly to Example 1 from 3-(4-{[4-[5-fluoro-2-(methyloxy)phenyl]-2-hydroxy-4-methyl-2-(trifluoromethyl)pentyl]amino}-6-methyl-1H-indazol-1-yl)benzoic acid and D-prolinamide.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178573B2
Source datasetuspto-grants-2012_05
ORD IDord-1fdce2fac6de45f98cb5be3394097d1c
Source noteuspto-grants-2012_05