HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Nitro-3-trifluoromethyl-phenoxyethyl acetate → 4-Amino-3-trifluoromethyl-phenoxyethyl acetate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Nitro-3-trifluoromethyl-phenoxyethyl acetate | HCID 67520014 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | HCID 178418390 | HCID 178418390 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | 4-Amino-3-trifluoromethyl-phenoxyethyl acetate | HCID 67519990 | 121.1% |
Reaction Steps
In the ethyl acetate (30 mL) solution of 4-nitro-3-trifluoromethyl-phenoxyethyl acetate (3.24 g (theoretical amount: 2.83 g, 9.66 mmol) which had been obtained in 1), 10% palladium carbon (0.3 g) was added and hydrogen was added. After the catalyst had been separated by filtration, the solvent was removed by distillation under reduced pressure and crude 4-amino-3-trifluoromethyl-phenoxyethyl acetate (BB03, 3.08 g (theoretical amount: 2.54 g)−100%) was obtained as oily matter.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178681B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-a286c5b8ceee469da9ab477546843315 |
| Source note | uspto-grants-2012_05 |