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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925641Generated: October 28, 2026

(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetate → 1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetate

https://huagongshe.com/reaction/1925641

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(4R,6R)-tert-Butyl-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-acetateHCID 2734288—
Reactant1-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dioneHCID 14757173—
Product1,1-Dimethylethyl (4R,6R)-6-[2-[2-(4-fluorophenyl)-5-(1-methylethyl)-3-phenyl-1H-pyrrol-1-yl]ethyl]-2,2-dimethyl-1,3-dioxane-4-acetateHCID 66842234—

Reaction Steps

According to the same method as described in Example 4-1, the title compound was synthesized using 1-(4-fluorophenyl)-5-methyl-2-phenyl-1,4-hexanedione and t-butyl 2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxane-4-yl)acetate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178697B2
Source datasetuspto-grants-2012_05
ORD IDord-8488045145eb4278bff9d991a9ea5f35
Source noteuspto-grants-2012_05