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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1925642Generated: October 26, 2026

2-[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic Acid → 2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid

https://huagongshe.com/reaction/1925642

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-[(4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl]acetic AcidHCID 11790629—
Reactant1-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dioneHCID 14757173—
Product2-((4R,6R)-6-(2-(2-(4-fluorophenyl)-5-isopropyl-3-phenyl-1H-pyrrol-1-yl)ethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acidHCID 66841929—

Reaction Steps

According to the same method as in Example 4-1, the title compound was synthesized using 1-(4-fluorophenyl)-5-methyl-2-phenyl-1,4-hexanedione and 2-((4R,6R)-6-(2-aminoethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178697B2
Source datasetuspto-grants-2012_05
ORD IDord-4705a0df9f814f3c894a27035cd9ff60
Source noteuspto-grants-2012_05