1-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dione → HCID 66842091, compound

HRID 1925648Notes

Reaction equation

HRID 1925648 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH:9]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:10][C:11](=O)[CH:12]([CH3:14])[CH3:13])=[CH:4][CH:3]=1.[NH2:23][CH2:24][CH2:25][C@H:26]1[O:31][B:30]([CH2:32][CH3:33])[O:29][C@@H:28]([CH2:34][C:35]([O:37][C:38]([CH3:41])([CH3:40])[CH3:39])=[O:36])[CH2:27]1>>[CH2:32]([B:30]1[O:29][C@@H:28]([CH2:34][C:35]([O:37][C:38]([CH3:39])([CH3:40])[CH3:41])=[O:36])[CH2:27][C@@H:26]([CH2:25][CH2:24][N:23]2[C:11]([CH:12]([CH3:14])[CH3:13])=[CH:10][C:9]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:8]2[C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[O:31]1)[CH3:33]

Participants

3

Reactant 2

HCID 147571731-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dioneHCID 66842166HCID 66842166, compound

Product 1

HCID 66842091HCID 66842091, compound

Procedure

According to the same method as in Example 4-1, the title compound was synthesized using 1-(4-fluorophenyl)-5-methyl-2-phenyl-1,4-hexanedione and t-butyl 2-((4R,6R)-6-(2-aminoethyl)-2-ethyl-1,3,2-dioxaborinan-4-yl)acetate.

Sources & evidence

ORD record
ord-3325c4e796694450b9e9942a8fce762a
Source dataset
uspto-grants-2012_05
Patent number
US08178697B2

Reaction notes

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