1-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dione → HCID 66842145, compound

HRID 1925650Notes

Reaction equation

HRID 1925650 reaction equation
[F:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=O)[CH:9]([C:16]2[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=2)[CH2:10][C:11](=O)[CH:12]([CH3:14])[CH3:13])=[CH:4][CH:3]=1.[NH2:23][CH2:24][CH2:25][CH:26]1[O:31][C:30](=[O:32])[CH2:29][CH:28]([O:33][CH2:34][C:35]2[CH:40]=[CH:39][CH:38]=[CH:37][CH:36]=2)[CH2:27]1>>[CH2:34]([O:33][CH:28]1[CH2:27][CH:26]([CH2:25][CH2:24][N:23]2[C:11]([CH:12]([CH3:14])[CH3:13])=[CH:10][C:9]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)=[C:8]2[C:5]2[CH:6]=[CH:7][C:2]([F:1])=[CH:3][CH:4]=2)[O:31][C:30](=[O:32])[CH2:29]1)[C:35]1[CH:36]=[CH:37][CH:38]=[CH:39][CH:40]=1

Participants

3

Reactant 2

HCID 147571731-(4-Fluorophenyl)-5-methyl-2-phenylhexane-1,4-dioneHCID 66841988HCID 66841988, compound

Product 1

HCID 66842145HCID 66842145, compound

Procedure

According to the same method as in Example 4-1, the title compound was synthesized using 1-(4-fluorophenyl)-5-methyl-2-phenyl-1,4-hexanedione and 6-(2-aminoethyl)-4-(benzyloxy)tetrahydro-2H-pyran-2-one.

Sources & evidence

ORD record
ord-7afa451987b04140b641f35f01473866
Source dataset
uspto-grants-2012_05
Patent number
US08178697B2

Reaction notes

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