Hydrochloric Acid → HCID 25183367, compound

Participants

Reaction Steps

To a solution of 91 (176 mg; 0.42 mmol) in acetonitrile (2 mL) was added aqueous sodium hydroxide (0.83 mL; 2N). The resulting mixture was stirred overnight at room temperature. The reaction mixture was acidified with aqueous hydrochloric acid (2N) and extracted with ethyl acetate. The organic layer was dried over sodium sulfate, decanted, and concentrated under reduced pressure. The desired product was obtained as fine needles from dichloromethane and hexanes as a greenish-yellow solid (137 mg).

Provenance & Evidence