Chlorosulfonic acid → HCID 59180414, compound

HRID 1925731Notes

Reaction equation

HRID 1925731 reaction equation
[C:1]([C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([I:11])[CH:6]=1)([CH3:4])([CH3:3])[CH3:2].Cl[S:13]([OH:16])(=[O:15])=[O:14]>ClCCl>[C:1]([C:5]1[CH:10]=[CH:9][C:8]([S:13]([OH:16])(=[O:15])=[O:14])=[C:7]([I:11])[CH:6]=1)([CH3:4])([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 24638Chlorosulfonic acidHCID 6379581-tert-butyl-3-iodobenzene

Product 1

HCID 59180414HCID 59180414, compoundYield 95.1%

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Synthesized as described for 1 using 1-tert-butyl-3-iodobenzene (9.65 g; 37.09 mmol), chlorosulfonic acid (3.20 mL; 48.22 mmol), and anhydrous dichloromethane (140 mL). Trituration of the crude product from hexanes yielded the title compound as a brown oil (12.0 g).

Workup

  1. customSynthesized

Sources & evidence

ORD record
ord-1e75d69e8fc84c3f8644320ddb5927e4
Source dataset
uspto-grants-2012_05
Patent number
US08178699B2

Reaction notes

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