反应详情

Synthesized as described for 1 using 106 (830.0 mg; 5.45 mmol), chlorosulfonic acid (0.44 mL; 6.54 mmol) and anhydrous dichloromethane (25 mL). The crude gray solid obtained was washed with hexanes and dried under reduced pressure. This afforded a 3:1 regioisomeric mixture of the title compound and 2-tert-butyl-4-fluorobenzenesulfonic acid (960 mg).

1. customSynthesized
2. customThe crude gray solid obtained
3. washwas washed with hexanes
4. customdried under reduced pressure
5. customThis afforded