HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → HCID 67521542, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | HCID 67520294 | HCID 67520294 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 67521542 | HCID 67521542 | 66.7% |
Reaction Steps
Synthesized as described for 22 using 166 (25.0 mg, 0.049 mmol), tetrahydrofuran (1 mL) and aqueous hydrochloric acid (1 mL). Purification by automated silica gel column chromatography (Biotage®) eluting with ethyl acetate/hexanes (0 to 30% v/v over 400 mL gradient elution) yielded the title product as a clear oil (15.2 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08178699B2 |
| Source dataset | uspto-grants-2012_05 |
| ORD ID | ord-f9f5f1d73cae4826850b98ebac87c82e |
| Source note | uspto-grants-2012_05 |