O-Phenylenediamine → HCID 53354006, compound

Participants

Reaction Steps

6-(2-(9H-thioxanthen-9-ylidene)acetamido)hexanoic acid (367 mg, 1 mmol), and 8 ml of DMF were stirred at room temperature while 1-Ethyl-3-(3-dimethylaminopropyl)carbodi-imide hydrochloride (394 mg, 2 mmol), hydroxy-benzotriazole (162 mg, 1.2 mmol), triethylamine (404 mg, 4 mmol) and o-phenylenediamine (432 mg, 4 mmol) were added. The mixture was stirred for 24 hours at room temperature. The mixture was diluted with 400 mL of brine. The solids were collected by vacuum filtration, washed with water and dried under vacuum to give the title compound (302 mg, 66% yield) as a brown solid. LC-MS (m/z) 458 (M+1).

Provenance & Evidence