2,7-Dichlorobenzo[d]thiazole → HCID 44158821, compound

Participants

Reaction Steps

Same procedure as 3-(6-fluorobenzothiazol-2-yl)-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine except using 2,7-dichloro-1,3-benzothiazole in place of 2-chloro-6-fluorobenzothiazole to afford the title compound as a yellow solid. 1H NMR (400 MHz, DMSO-d6): δ=2.10-2.22 (m, 2H), 2.23-2.31 (m, 2H), 3.12 (q, J=11.1 Hz, 2H), 3.42 (d, J=12.4 Hz, 2H), 4.46-4.56 (m, 1H), 7.60-7.66 (m, 2H), 8.09 (s, 1H), 8.12 (dd, J=6.2, 2.9 Hz, 1H), 8.44 (s, 2H), 8.56 (d, J=1.8 Hz, 1H). MS (ES+): m/z=411.09/413.06 (3:1) [MH+]. HPLC: tR=2.16 min (ZQ2, polar—5 min).

Provenance & Evidence