HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926394Generated: November 3, 2026
2-Fluoro-5-(trifluoromethyl)aniline → 2-Chloro-4-(trifluoromethyl)-1,3-benzothiazole
https://huagongshe.com/reaction/1926394
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Fluoro-5-(trifluoromethyl)aniline | HCID 136349 | — |
| Reactant | 2,5-Dichloro-1,3-benzothiazole | HCID 13314816 | — |
| Reactant | HCID 178506125 | HCID 178506125 | — |
| Product | 2-Chloro-4-(trifluoromethyl)-1,3-benzothiazole | HCID 24728950 | — |
Reaction Steps
The title compound was prepared from 2-fluoro-5-trifluoromethylaniline via 2-mercapto-4-trifluoromethyl-1,3-benzothiazole as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 100° C. for 6 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US08178668B2 |
|---|
| Source dataset | uspto-grants-2012_05 |
|---|
| ORD ID | ord-8ff2a02ffbc94214a7f74de991f004d1 |
|---|
| Source note | uspto-grants-2012_05 |
|---|
