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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926404Generated: October 30, 2026

3-Amino-4-chlorobenzonitrile → 2-Chlorobenzo[d]thiazole-5-carbonitrile

https://huagongshe.com/reaction/1926404

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Amino-4-chlorobenzonitrileHCID 104464—
Reactant2,5-Dichloro-1,3-benzothiazoleHCID 13314816—
ReactantHCID 178509540HCID 178509540—
Product2-Chlorobenzo[d]thiazole-5-carbonitrileHCID 21985679—

Reaction Conditions

Temperature95 °C

Reaction Steps

The title compound was prepared from 3-amino-4-chlorobenzonitrile via 2-mercapto-1,3-benzothiazole-5-carbonitrile as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 95° C. for 10 h.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08178668B2
Source datasetuspto-grants-2012_05
ORD IDord-15e65cc7efa543439f5a4dd18ea3073c
Source noteuspto-grants-2012_05