HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1926406Generated: November 2, 2026
4-Amino-3-chlorobenzonitrile → 2-Chloro-1,3-benzothiazole-6-carbonitrile
https://huagongshe.com/reaction/1926406
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 4-Amino-3-chlorobenzonitrile | HCID 519896 | — |
| Reactant | 2,5-Dichloro-1,3-benzothiazole | HCID 13314816 | — |
| Reactant | 2-Sulfanylidene-2,3-dihydro-1,3-benzothiazole-6-carbonitrile | HCID 178509504 | — |
| Product | 2-Chloro-1,3-benzothiazole-6-carbonitrile | HCID 21985859 | — |
Reaction Steps
The title compound was prepared from 4-amino-3-chlorobenzonitrile via 2-mercapto-1,3-benzothiazole-6-carbonitrile as described for 2,5-dichloro-1,3-benzothiazole except that in the first step the reaction mixture was heated to 120° C. for 12 h.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US08178668B2 |
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| Source dataset | uspto-grants-2012_05 |
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| ORD ID | ord-5c50be31205b46e39585702495995ccb |
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| Source note | uspto-grants-2012_05 |
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