HRID1926419
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
PROCEDURE
实验过程
Following the procedure for 3-(7-fluoro-4-trifluoromethylbenzothiazol-2-yl)-5-(1-piperidin-4-yl-1H-pyrazol-4-yl)-pyridin-2-ylamine, using 2-chloro-4,5-difluoro-1,3-benzothiazole and conducting the Suzuki coupling at 80° C. for 3 h, the title compound was obtained as a yellow solid. MS (ES+): m/z=413.13 [MH+]. HPLC: tR=2.46 min (ZQ3, polar—5 min).
WORKUP
后处理
- customat 80° C.
- customfor 3 h