Benzene → HCID 86596158, compound

Participants

Reaction Steps

84 mg (0.36 mmol) of 4-(2′-cyanoisoindolyl)aniline was suspended in 40 mL of a mixture of benzene and tetrahydrofuran (1:1, v/v) and refluxed for 1 hour in the presence of 65 mg (0.64 mmol) of triethylamine and 40 mg (0.35 mmol) of thiophosgene. The reaction mixture was concentrated under a vacuum, and then the residue was recrystallized with acetonitrile to obtain 37 mg of the titled 4-(2′-cyanoisoindolyl)phenylisothiocyanate expressed by the following formula in the form of a colorless needle crystal.

Provenance & Evidence