3-(Bromomethyl)-2-nitropyridine → HCID 59627180, compound

Participants

Reaction Steps

Ethyl 2-(diphenylmethyleneamino)-3-[2-nitro-3-(trifluoromethyl)phenyl]propanoate (18) Ethyl 2-(diphenylmethyleneamino)-3-[2-nitro-3-(trifluoromethyl)phenyl]propanoate (18) was prepared according to the general procedure for the synthesis of ethyl 2-(diphenylmethyleneamino)-3-(2-nitropyridin-3-yl)propanoate (5) in Example 1, except that 1-(bromomethyl)-2-nitro-3-(trifluoromethyl)benzene (17) from the previous step was used in place of 3-(bromomethyl)-2-nitropyridine (3) (Yield: 3.2 g, 28% over 2 steps).

Provenance & Evidence