Hydrochloric Acid → HCID 58016854, compound

Participants

Reaction Steps

Dissolve 30 mg (0.07 mmol) 6-{[5-(4-methylphenyl)-6-phenylfuro[2,3-d]pyrimidin-4-yl]amino}-hexanoic acid methyl ester in 0.1 ml methanol, 0.05 ml THF and one drop of water, and add 0.1 ml of 2.5 M sodium hydroxide solution. Stir the mixture for 1 h at RT and then lightly acidify with 1 N hydrochloric acid. Filter off the precipitate with suction, wash several times with water, and dry at high vacuum. 28 mg (96.5% of theor.) of the target compound is obtained.

Provenance & Evidence