Carbon Tetrachloride → 3-Phenoxybenzyl chloride

Participants

Reaction Steps

To a solution of carbon tetrachloride (40 mL) of (3-phenoxy-phenyl)-methanol (2.0 g) was added triphenylphosphine (3.2 g) at room temperature, which was heated to reflux under a nitrogen atmosphere for 5 hours and 40 minutes. The reaction mixture was cooled to room temperature and the solvent was evaporated under a reduced pressure. The residue was purified by silica gel column chromatography (heptane:ethyl acetate=10:1) to obtain the titled compound (2.1 g).

Provenance & Evidence