Nitric Acid → HCID 86628846, compound

HRID 1927583Notes

Reaction equation

HRID 1927583 reaction equation
[N+:1]([O-:4])([OH:3])=[O:2].[NH2:5][C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][C:9](=[O:11])[NH2:10].[N+:15]([O-:18])([OH:17])=[O:16].[NH2:19][C@H:20]([C:26]([OH:28])=[O:27])[CH2:21][CH2:22][C:23](=[O:25])[NH2:24]>O>[N+:1]([O-:4])([OH:3])=[O:2].[N+:15]([O-:18])([OH:17])=[O:16].[NH2:5][C@H:6]([C:12]([OH:14])=[O:13])[CH2:7][CH2:8][C:9](=[O:11])[NH2:10].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[N+:1]([O-:4])([OH:3])=[O:2].[NH2:19][C@H:20]([C:26]([OH:28])=[O:27])[CH2:21][CH2:22][C:23](=[O:25])[NH2:24]

Participants

6

Reactant 3

HCID 944Nitric AcidHCID 5961L-GlutamineHCID 86628848HCID 86628848, compound

Product 2

HCID 86628846HCID 86628846, compoundHCID 86628847HCID 86628847, compound

Reagents, catalysts & solvents 1

HCID 962WaterSolvent

Procedure

Applicants have cost-effectively synthesized Glutamine Nitrate by combining nitric acid and Glutamine, mixing with water, and leaving to crystallize. Further nitratization can take place, yielding Glutamine Dinitrate or Glutamine Trinitrate. An alternative implementation comprises using Nitrous Acid (HNO2) instead of Nitric Acid (HNO3), thus yielding Glutamine Nitrite. Glutamine Nitrite has the same effects as Glutamine Nitrate, the only difference being that it requires one less step to yield Nitric Oxide (NO—). Mixed salts may also be used, such as in the non-limiting example of Glutamine Nitrate-Orotate.

Workup

  1. customleaving
  2. customto crystallize

Sources & evidence

ORD record
ord-c377fe8cf1e74fb9b6ad9f6f2898b89a
Source dataset
uspto-grants-2012_05
Patent number
US08183288B2

Reaction notes

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