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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927671Generated: November 1, 2026

Dichloromethane → HCID 178442446, compound

https://huagongshe.com/reaction/1927671

Reaction equation

Participants

RoleNameHCIDCharge
ReactantDichloromethaneHCID 6344—
ReactantAmmonium HydroxideHCID 14923—
ReactantHCID 178442448HCID 178442448—
ProductHCID 178442446HCID 178442446—

Reaction Steps

3-[4-(2,2-dimethylbutyl)-1H-imidazol-2-yl]propanoyl chloride in methylene chloride (0.3 M) (7.8 mL, 2.3 mmol) was added to a rapidly stirred solution of concentrated aqueous ammonium hydroxide (2.5 mL) at 0° C. After stirring at rt for 1 h, the volatiles were removed to afford the title compound, which was used without further purification.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183275B2
Source datasetuspto-grants-2012_05
ORD IDord-10479eb569194d9fa7f4d845742d72e0
Source noteuspto-grants-2012_05