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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1927790Generated: November 1, 2026

Trifluoroacetic acid → HCID 59403217, compound

https://huagongshe.com/reaction/1927790

Reaction equation

Participants

RoleNameHCIDCharge
ReactantTrifluoroacetic acidHCID 6422—
ReactantHCID 68469003HCID 68469003—
SolventDichloromethaneHCID 6344—
ProductHCID 59403217HCID 59403217111.5%

Reaction Steps

tert-Butyl 2-(4-(4-((2,6-dichlorophenethyl)carbamoyl)phenoxy)-3-cyanophenyl)acetate (34 mg, 0.065 mmol) was dissolved in dichloromethane (1 ml) and TFA (1 ml) was added. After stirring for 45 minutes, the mixture was concentrated under reduced pressure to give 2-(3-cyano-4-(4-(2,6-dichlorophenethylcarbamoyl)phenoxy)phenyl)acetic acid (0.034 g).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08183289B2
Source datasetuspto-grants-2012_05
ORD IDord-b3d1894e87d94811812afa7943b7f363
Source noteuspto-grants-2012_05